Neuroendocrine Select Abstracts
Select highlights of recent findings in neuroendocrine cancer treatment and research presented monthly and which may include clinical trial results, research findings, cancer treatment studies and those addressing other issues which are of interest.
These presentations are NOT meant to be taken as recommendations in any manner, but rather are offered to help provide a sense of the growing edge of cancer research as pertaining to neuroendocrine treatment, diagnosis and care. And also to give attention to some of the more current interesting, unusual or even offbeat studies. Please read the Pancreatica Disclaimer.
Phase II study of first-line FOLFIRI for progressive metastatic well-differentiated pancreatic endocrine carcinoma.
Brixi-Benmansour H, Jouve JL, Mitry E, Bonnetain F, Landi B, Hentic O, Bedenne L, Cadiot G.
Dig Liver Dis. 2011 Nov;43(11):912-6. PMID: 21831734
Link to Abstract
EUS-FNA for Pancreatic Neuroendocrine Tumors: A Tertiary Cancer Center Experience.
Atiq M, Bhutani MS, Bektas M, Lee JE, Gong Y, Tamm EP, Shah CP, Ross WA, Yao J, Raju GS, Wang X, Lee JH.
Dig Dis Sci. 2011 Oct 1. [Epub] PMID: 21964743
Link to Abstract
New therapeutic options for metastatic malignant insulinomas.
de Herder WW, van Schaik E, Kwekkeboom D, Feelders RA.
Clin Endocrinol (Oxf). 2011 Sep;75(3):277-84.
PMID: 21649688
Link to Abstract
Prognostic validity of a novel american joint committee on cancer staging classification for pancreatic neuroendocrine tumors.
Strosberg JR, Cheema A, Weber J, Han G, Coppola D, Kvols LK.
J Clin Oncol. 2011 Aug 1;29(22):3044-9. PMID: 21709192
Link to Abstract
Tumor size correlates with malignancy in nonfunctioning pancreatic endocrine tumor.
Bettini R, Partelli S, Boninsegna L, Capelli P, Crippa S, Pederzoli P, Scarpa A, Falconi M.
Surgery. 2011 Jul;150(1):75-82. PMID: 21683859
Link to Abstract
Response by Choi criteria to sunitinib plus octreotide LAR in a functional heavily pretreated advanced pancreatic neuroendocrine tumor.
Grande E, José Díez J, Pachón V, Angeles Vaz M, Longo F, Guillén C, García de Paredes ML, Carrato A.
Anticancer Drugs. 2011 Jun;22(5):477-9. PMID: 21346550
Link to Abstract
Pancreatic endocrine tumors with major vascular abutment, involvement, or encasement and indication for resection.
Norton JA, Harris EJ, Chen Y, Visser BC, Poultsides GA, Kunz PC, Fisher GA, Jensen RT.
Arch Surg. 2011 Jun;146(6):724-32. PMID: 21690450
Link to Abstract
Treatment with somatostatin analogues and chemoembolization of liver metastases for severe hypoglycemia in malignant insulinomas.
Maiza JC, Vezzosi D, Grunenwald S, Otal P, Guimbaud R, Bennet A, Caron P.
J Endocrinol Invest. 2011 May 27. [Epub] PMID: 21623151
Link to Abstract
First-line treatment of patients with disseminated poorly differentiated neuroendocrine carcinomas with carboplatin, etoposide, and vincristine: A single institution experience.
Olsen IH, Langer SW, Jepsen I, Assens M, Federspiel B, Hasselby JP, Hansen CP, Kjær A, Knigge U.
Acta Oncol. 2011 May 26. [Epub] PMID: 21615243
Link to Abstract
Implications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomes.
Haynes AB, Deshpande V, Ingkakul T, Vagefi PA, Szymonifka J, Thayer SP, Ferrone CR, Wargo JA, Warshaw AL, Fernández-del Castillo C.
Arch Surg. 2011 May;146(5):534-8. PMID: 21576607
Link to Abstract
Liver transplantation for hepatic metastases of neuroendocrine pancreatic tumors: a survival-based analysis.
Máthé Z, Tagkalos E, Paul A, Molmenti EP, Kóbori L, Fouzas I, Beckebaum S, Sotiropoulos GC.
Transplantation. 2011 Mar 15;91(5):575-82. PMID: 21200365
Link to Abstract
Everolimus for advanced pancreatic neuroendocrine tumors.
Yao JC, Shah MH, Ito T, Bohas CL, Wolin EM, Van Cutsem E, Hobday TJ, Okusaka T, Capdevila J, de Vries EG, Tomassetti P, Pavel ME, Hoosen S, Haas T, Lincy J, Lebwohl
D, Öberg K; RAD001 in Advanced Neuroendocrine Tumors, Third Trial (RADIANT-3) Study Group.
N Engl J Med. 2011 Feb 10;364(6):514-23. PMID: 21306238
Sunitinib malate for the treatment of pancreatic neuroendocrine tumors.
Raymond E, Dahan L, Raoul JL, Bang YJ, Borbath I, Lombard-Bohas C, Valle J, Metrakos P, Smith D, Vinik A, Chen JS, Hörsch D, Hammel P, Wiedenmann B, Van Cutsem E, Patyna S, Lu DR, Blanckmeister C, Chao R, Ruszniewski P.
N Engl J Med. 2011 Feb 10;364(6):501-13. PMID: 21306237
Link to Abstract
Phase II study of radiopeptide 177Lu-octreotate and capecitabine therapy of progressive disseminated neuroendocrine tumours.
Claringbold PG, Brayshaw PA, Price RA, Turner JH.
Eur J Nucl Med Mol Imaging. 2011 Feb;38(2):302-11. PMID: 21052661
Link to Abstract
First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.
Strosberg JR, Fine RL, Choi J, Nasir A, Coppola D, Chen DT, Helm J, Kvols L.
Cancer. 2011 Jan 15;117(2):268-75. Epub 2010 Sep 7. PMID: 20824724
Link to Abstract
Response to temozolomide and bevacizumab in a patient with poorly differentiated neuroendocrine carcinoma.
Lindholm DP, Eriksson B, Granberg D.
Med Oncol. 2010 Dec 30. [Epub] PMID: 21191667
Link to Abstract
Laparoscopic radiofrequency thermal ablation of neuroendocrine hepatic metastases: long-term follow-up.
Akyildiz HY, Mitchell J, Milas M, Siperstein A, Berber E.
Surgery. 2010 Dec;148(6):1288-93; discussion 1293. PMID: 21134563
Link to Abstract
Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysis.
Mayo SC, de Jong MC, Pulitano C, Clary BM, Reddy SK, Gamblin TC, Celinksi SA, Kooby DA, Staley CA, Stokes JB, Chu CK, Ferrero A, Schulick RD, Choti MA, Mentha G, Strub J, Bauer TW, Adams RB, Aldrighetti L, Capussotti L, Pawlik TM.
Ann Surg Oncol. 2010 Dec;17(12):3129-36. 2010 Jun 29. [Epub] PMID: 20585879
Link to Abstract
Hepatic artery chemoembolization for the treatment of liver metastases from neuroendocrine tumors: a long-term follow-up in 123 patients.
Dong XD, Carr BI.
Med Oncol. 2010 Nov 24. [Epub] PMID: 21107755
Link to Abstract
Evaluation of the combination 5-Fluorouracil, dacarbazine, and epirubicin in patients with advanced well-differentiated neuroendocrine tumors.
Walter T, Bruneton D, Cassier PA, Hervieu V, Pilleul F, Scoazec JY, Chayvialle JA, Lombard-Bohas C.
Clin Colorectal Cancer. 2010 Oct 1;9(4):248-54.PMID: 20920998
Link to Abstract
First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.
Strosberg JR, Fine RL, Choi J, Nasir A, Coppola D, Chen DT, Helm J, KvolsL.
Cancer. 2010 Sep 7. [Epub] PMID: 20824724
Link to Abstract
Poorly differentiated endocrine carcinoma of the pancreas responded to gemcitabine: Case report.
Nakazuru S, Yoshio T, Suemura S, Itoh M, Araki M, Yoshioka C, Ohta M, Sueyoshi Y, Ohta T, Hasegawa H, Morita K, Toyama T, Kuzushita N, Kodama Y, Mano M, Mita E.
World J Gastroenterol. 2010 Aug 14;16(30):3853-6.PMID: 20698050
Link to Abstract
Pancreatic endocrine tumors less than 4 cm in diameter: resect or enucleate? a single-center experience.
Casadei R, Ricci C, Rega D, D’Ambra M, Pezzilli R, Tomassetti P, Campana D, Nori F, Minni F.
Pancreas. 2010 Aug;39(6):825-8.PMID: 20431423
Link to Abstract
Chromogranin A–biological function and clinical utility in neuro endocrine tumor disease.
Modlin IM, Gustafsson BI, Moss SF, Pavel M, Tsolakis AV, Kidd M.
Ann Surg Oncol. 2010 Mar 9. [Epub ahead of print]PMID: 20217257
Link to Abstract
Salvage therapy with (177)Lu-octreotate in patients with bronchial and gastroenteropancreatic neuroendocrine tumors.
van Essen M, Krenning EP, Kam BL, de Herder WW, Feelders RA, Kwekkeboom DJ.
J Nucl Med. 2010 Mar;51(3):383-90. Epub 2010 Feb 11.PMID: 20150247
Link to Abstract
90Y-edotreotide for metastatic carcinoid refractory to octreotide.
Bushnell DL Jr, O’Dorisio TM, O’Dorisio MS, Menda Y, Hicks RJ, Van Cutsem E, Baulieu JL, Borson-Chazot F, Anthony L, Benson AB, Oberg K, Grossman AB, Connolly M, Bouterfa H, Li Y, Kacena KA, Lafrance N, Pauwels SA.
J Clin Oncol. 2010 Mar 1. [Epub ahead of print]PMID: 20194865
Link to Abstract
177Lu-[DOTA0,Tyr3] octreotate therapy in patients with disseminated neuroendocrine tumors: Analysis of dosimetry with impact on future therapeutic strategy.
Garkavij M, Nickel M, Sjögreen-Gleisner K, Ljungberg M, Ohlsson T, Wingårdh K, Strand SE, Tennvall J.
Cancer. 2010 Feb 15;116(4 Suppl):1084-92.PMID: 20127957
Link to Abstract
Treatment with tandem [(90)Y]DOTA-TATE and [(177)Lu] DOTA-TATE of neuroendocrine tumors refractory to conventional therapy: preliminary results.
Seregni E, Maccauro M, Coliva A, Castellani MR, Bajetta E, Aliberti G, Vellani C, Chiesa C, Martinetti A, Bogni A, Bombardieri E.
Q J Nucl Med Mol Imaging. 2010 Feb;54(1):84-91.PMID: 20168290
Link to Abstract
Efficacy of using a Standard Activity of (131)I-MIBG Therapy in Patients with Disseminated Neuroendocrine Tumours.
Navalkissoor S, Alhashimi DM, Quigley AM, Caplin ME, Buscombe JR.
Eur J Nucl Med Mol Imaging. 2009 Dec 17. [Epub ahead of print]PMID: 20016892
Link to Abstract
Neoadjuvant Peptide Receptor Radionuclide Therapy for an Inoperable Neuroendocrine Pancreatic Tumor.
Kaemmerer D, Prasad V, Daffner W, Hörsch D, Klöppel G, Hommann M, Baum RP.
World J Gastroenterol. 2009 Dec 14;15(46):5867-70.PMID: 19998512
Link to Abstract
A Successful Two-Stage Treatment with CDDP and CPT-11 for Pancreatic Neuroendocrine Carcinoma with Liver Metastasis.
Nomura S, Togawa A, Kaiho T, Shinmura K, Yanagisawa S, Okamoto R, Nishimura M, Tsuchiya S, Miyazaki M.
Gan To Kagaku Ryoho. 2009 Nov;36(11):1897-900. Japanese. PMID: 19920396
Link to Abstract
Refractory Neuroendocrine Tumor-Response to Liposomal Doxorubicin and Capecitabine.
Masi G, Fornaro L, Cupini S, Loupakis F, Vasile E, Baldi GG, Stasi I, Salvatore L, Falcone A.
Nat Rev Clin Oncol. 2009 Nov;6(11):670-4.PMID: 19861994
Link to Abstract
Combined Liver Surgery and RFA for Patients with Gastroenteropancreatic Endocrine Tumors Presenting with More Than 15 Metastases to the Liver.
Elias D, Goéré D, Leroux G, Dromain C, Leboulleux S, de Baere T, Ducreux
M, Baudin E.
Eur J Surg Oncol. 2009 Oct;35(10):1092-7. Epub 2009 May 21.PMID: 19464140
Link to Abstract
High-Dose Octreotide Acetate for Management of Gastroenteropancreatic Neuroendocrine Tumors.
Chadha MK, Lombardo J, Mashtare T, Wilding GE, Litwin A, Raczyk C, Gibbs JF, Kuvshinoff B, Javle MM, Iyer RV.
Anticancer Res. 2009 Oct;29(10):4127-30.PMID: 19846960
Link to Abstract
High-Administered Activity In-111 Octreotide Therapy with Concomitant Radiosensitizing 5FU Chemotherapy for Treatment of Neuroendocrine Tumors: Preliminary Experience.
Kong G, Johnston V, Ramdave S, Lau E, Rischin D, Hicks RJ.
Cancer Biother Radiopharm. 2009 Oct;24(5):527-33.PMID: 19877882
Link to Abstract
Pancreatic Islet Cell Carcinoma Presenting with Concurrent Cushing’s and Zollinger-Ellison Syndromes: Case Series and Literature Review.
Said R, O’reilly EM, Blumgart L, Shia J, Abou-Alfa GK.
Eur J Gastroenterol Hepatol. 2009 Sep 18. [Epub]. PMID: 19770666
Link to Abstract
Detection of Unknown Primary Neuroendocrine Tumours (CUP-NET) using (68)Ga-DOTA-NOC Receptor PET/CT.
Prasad V, Ambrosini V, Hommann M, Hoersch D, Fanti S, Baum RP.
Eur J Nucl Med Mol Imaging. 2009 Jul 18. [Epub]. PMID: 19618183
Link to Abstract
Successful Control of Intractable Hypoglycemia Using Rapamycin in an 86-year old man with a Pancreatic Insulin-Secreting Islet Cell Tumor and Metastases.
Bourcier ME, Sherrod A, Diguardo M, Vinik AI.
J Clin Endocrinol Metab. 2009 Jun 30. [Epub] PMID: 19567519
Link to Abstract
Staged Surgery with Neoadjuvant (90)Y-DOTATOC Therapy for Down-Sizing Synchronous Bilobular Hepatic Metastases from a Neuroendocrine Pancreatic Tumor.
Stoeltzing O, Loss M, Huber E, Gross V, Eilles C, Mueller-Brand J, Schlitt HJ.
Langenbecks Arch Surg. 2009 Jun 9. [Epub] PMID: 19506898
Link to Abstract
Prolonged Survival After Hepatic Artery Embolization in Patients with Midgut Carcinoid Syndrome.
Swärd C, Johanson V, Nieveen van Dijkum E, Jansson S, Nilsson O, Wängberg B, Ahlman H, Kölby L.
Br J Surg. 2009 May;96(5):517-21. PMID: 19358175
Link to Abstract
Laparoscopic Surgery for Pancreatic Insulinomas: A Single-Institution Experience of 29 Cases.
Luo Y, Liu R, Hu MG, Mu YM, An LC, Huang ZQ. J Gastrointest Surg. 2009
May;13(5):945-50. PMID: 19224293
Link to Abstract
Liver Resection Versus Other Treatments for Neuroendocrine Tumours in Patients with Resectable Liver Metastases.
Gurusamy KS, Ramamoorthy R, Sharma D, Davidson BR.
Cochrane Database Syst Rev. 2009 Apr 15;(2):CD007060. PMID: 19370671
Link to Abstract
Development of the Norfolk Quality of Life Tool for Assessing Patients with Neuroendocrine Tumors.
Vinik E, Carlton CA, Silva MP, Vinik AI.
Pancreas. 2009 Apr;38(3):e87-95. PMID: 19276865
Link to Abstract
Radiotherapy for Pancreatic Neuroendocrine Tumors.
Contessa JN, Griffith KA, Wolff E, Ensminger W, Zalupski M, Lawrence TS, Ben-Josef E.
Int J Radiat Oncol Biol Phys. 2009 Mar 25 [Epub]. PMID: 19327905
Link to Abstract
A Rare Surgical Case of Multiple Liver Resections for Recurrent Liver Metastases from Pancreatic Gastrinoma: Liver and Vena Cava Resection.
Pachera S, Yokoyama Y, Nishio H, Oda K, Ebata T, Igami T, Abe T, Shingu Y, Nagino M.
J Hepatobiliary Pancreat Surg. 2009 Mar 10 [Epub]. PMID: 19267257
Link to Abstract
Management of the Primary Tumor in Patients with Metastatic Pancreatic Neuroendocrine Tumor: A Contemporary Single-Institution Review.
Bruzoni M, Parikh P, Celis R, Are C, Ly QP, Meza JL, Sasson AR.
Am J Surg. 2009 Mar;197(3):376-81. PMID: 19245918
Link to Abstract
Reclassification of Neuroendocrine Tumors Improves the Separation of Carcinoids and the Prediction of Survival.
Skov BG, Krasnik M, Lantuejoul S, Skov T, Brambilla E.
J Thorac Oncol. 2008 Dec;3(12):1410-5. PMID: 19057265
Link to Abstract
Combination Therapy with Histone Deacetylase Inhibitors and Lithium Chloride: A Novel Treatment for Carcinoid Tumors.
Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H.
Ann Surg Oncol. 2008 Nov 22. [Epub]. PMID: 19030935
Link to Abstract
Intraoperative Hand Held Gamma Probe Detection of a Recurrent Nonfunctional Neuroendocrine Tumor.
Van Haren RM, Fitzgerald TL.
JOP. 2008 Nov 3;9(6):704-7. PMID: 18981551
Link to Abstract
Laparoscopic Enucleation of a Nonfunctioning Neuroendocrine Tumor of the Pancreas.
Kang CM, Lee KG, Pyo JY, Lee SW, Kim KS, Choi JS, Lee WJ, Kim BR.
Yonsei Med J. 2008 Oct 31;49(5):864-8. PMID: 18972611
Link to Abstract
Surgical Approach and Perioperative Complications Determine Short-Term Outcomes in Patients with Insulinoma: Results of a Bi-Institutional Study.
Roland CL, Lo CY, Miller BS, Holt S, Nwariaku FE.
Ann Surg Oncol. 2008 Sep 30. [Epub] PMID: 18825460
Link to Abstract
Clinical Applications of 68Ga-DOTANOC in Neuroendocrine Tumours.
Lopci E, Nanni C, Rampin L, Rubello D, Fanti S.
Minerva Endocrinol. 2008 Sep;33(3):277-81. PMID: 18846030
Link to Abstract
Risk Factors Associated with Neuroendocrine Tumors: A U.S.-Based Case-Control Study.
Hassan MM, Phan A, Li D, Dagohoy CG, Leary C, Yao JC.
Int J Cancer. 2008 Aug 15;123(4):867-73. PMID: 18491401
Link to Abstract
Radioembolization with Selective Internal radiation Microspheres for Neuroendocrine Liver Metastases.
King J, Quinn R, Glenn DM, Janssen J, Tong D, Liaw W, Morris DL.
Cancer. 2008 Jul 10. PMID: 18618495
Link to Abstract
Activity of Sunitinib in Patients with Advanced Neuroendocrine Tumors.
Kulke MH, Lenz HJ, Meropol NJ, Posey J, Ryan DP, Picus J, Bergsland E, Stuart K, Tye L, Huang X, Li JZ, Baum CM, Fuchs CS.<
J Clin Oncol. 2008 Jul 10;26(20):3403-10. PMID: 18612155
Link to Abstract
Prognostic Factors of Long-Term Outcome in Gastroenteropancreatic Neuroendocrine Tumours.
Pape UF, Berndt U, Mueller-Nordhorn J, Boehmig M, Roll S, Koch M, Willich S, Wiedenmann B.
Endocr Relat Cancer. 2008 Jul 4. PMID: 18603570
Link to Abstract
Clinical Value of Monitoring Plasma Octreotide Levels During Chronic Octreotide Long-Acting Repeatable Therapy in Carcinoid Patients.
Woltering EA, Salvo VA, O’Dorisio TM, Lyons J 3rd, Li G, Zhou Y, Seward JR, Go VL, Vinik AI, Mamikunian P, Mamikunian G.
Pancreas. 2008 Jul;37(1):94-100. PMID: 18580450
Link to Abstract
Selective Hepatic arterial Infusion of In-111-DTPA-Phe(1)-Octreotide in Neuroendocrine Liver Metastases.
Limouris GS, Chatziioannou A, Kontogeorgakos D, Mourikis D, Lyra M, Dimitriou P, Stavraka A, Gouliamos A, Vlahos L.
Eur J Nucl Med Mol Imaging. 2008 Jun 7. [Epub ahead of print] PMID: 18536916
Link to Abstract
Radioembolization for Unresectable Neuroendocrine Hepatic Metastases Using Resin 90Y-Microspheres: Early Results in 148 Patients.
Kennedy AS, Dezarn WA, McNeillie P, Coldwell D, Nutting C, Carter D, Murthy R, Rose S, Warner RR, Liu D, Palmedo H, Overton C, Jones B, Salem R.
Am J Clin Oncol. 2008 Jun;31(3):271-9. PMID: 18525307
Link to Abstract
Risk Factors Associated with Neuroendocrine Tumors: A U.S.-Based Case-Control Study.
Hassan MM, Phan A, Li D, Dagohoy CG, Leary C, Yao JC.
Int J Cancer. 2008 May 19. [Epub]PMID: 18491401
Link to Abstract
Radiolabeled DOTATOC in Patients with Advanced Paraganglioma and Pheochromocytoma.
Forrer F, Riedweg I, Maecke HR, Mueller-Brand J.
Q J Nucl Med Mol Imaging. 2008 May 16. [Epub]PMID: 18480742
Link to Abstract
Primary Tumour Resection in Metastatic Nonfunctioning Pancreatic Endocrine Carcinomas.
Bettini R, Mantovani W, Boninsegna L, Crippa S, Capelli P, Bassi C, Scarpa A, Pederzoli P, Falconi M.
Dig Liver Dis. 2008 May 5. [Epub] PMID: 18463008
Link to Abstract
Treatment with the Radiolabeled Somatostatin Analog [177 Lu-DOTA 0,Tyr3]Octreotate: Toxicity, Efficacy, and Survival.
Kwekkeboom DJ, de Herder WW, Kam BL, van Eijck CH, van Essen M, Kooij PP, Feelders RA, van Aken MO, Krenning EP.
J Clin Oncol. 2008 May 1;26(13):2124-30. PMID: 18445841
Link to Abstract
Surgery and Radiofrequency Ablation for Treatment of Liver Metastases from Midgut and Foregut Carcinoids and Endocrine Pancreatic Tumors.
Eriksson J, Stålberg P, Nilsson A, Krause J, Lundberg C, Skogseid B, Granberg D, Eriksson B, Akerström G, Hellman P.
World J Surg. 2008 May;32(5):930-8. PMID: 18324347
Link to Abstract
Comparison Between (68)Ga-DOTA-NOC and (18)F-DOPA PET for the Detection of Gastro-Entero-Pancreatic and Lung Neuro-Endocrine Tumours.
Ambrosini V, Tomassetti P, Castellucci P, Campana D, Montini G, Rubello D, Nanni C, Rizzello A, Franchi R, Fanti S.
Eur J Nucl Med Mol Imaging. 2008 Apr 17. [Epub]PMID: 18418596
Link to Abstract
Requiem for the Term ‘Carcinoid Tumour’ in the Gastrointestinal Tract?
Chetty R.
Can J Gastroenterol. 2008 Apr;22(4):357-8. PMID: 18414708
Link to Abstract
Improved Staging of Patients with Carcinoid and Islet Cell Tumors with 18F-Dihydroxy-Phenyl-Alanine and 11C-5-Hydroxy-Tryptophan Positron Emission Tomography.
http://www.ncbi.nlm.nih.gov/pubmed/18349401
J Clin Oncol. 2008 Mar 20;26(9):1489-95. PMID: 18349401
Link to Abstract
Pancreatic Cystic Neuroendocrine Tumors: Preoperative Diagnosis with Endoscopic Ultrasound and Fine-Needle Immunocytology.
Baker MS, Knuth JL, Dewitt J, Leblanc J, Cramer H, Howard TJ, Schmidt CM, Lillemoe KD, Pitt HA.
J Gastrointest Surg. 2008 Mar;12(3):450-6. PMID: 18157720
Link to Abstract
6-L-18F-Fluorodihydroxyphenylalanine PET in Neuroendocrine Tumors: Basic Aspects and Emerging Clinical Applications.
Jager PL, Chirakal R, Marriott CJ, Brouwers AH, Koopmans KP, Gulenchyn KY.
J Nucl Med. 2008 Apr;49(4):573-86. 2008 Mar 14. [Epub] PMID: 18344441
Link to Abstract
Targeting Vascular Endothelial Growth Factor in Advanced Carcinoid Tumor: A Random Assignment Phase II Study of Depot Octreotide with Bevacizumab and Pegylated Interferon Alpha-2b.
Yao JC, Phan A, Hoff PM, Chen HX, Charnsangavej C, Yeung SC, Hess K, Ng C, Abbruzzese JL, Ajani JA.
J Clin Oncol. 2008 Mar 10;26(8):1316-23. PMID: 18323556
Link to Abstract
Prognostic Score Predicting Survival after Resection of Pancreatic Neuroendocrine Tumors: Analysis of 3851 Patients.
Bilimoria KY, Talamonti MS, Tomlinson JS, Stewart AK, Winchester DP, Ko CY, Bentrem DJ.
Ann Surg. 2008 Mar;247(3):490-500. PMID: 18376195
Link to Abstract
Evaluation of Unusual Neuroendocrine Tumours by Means of (68)Ga-DOTA-NOC PET.
Fanti S, Ambrosini V, Tomassetti P, Castellucci P, Montini G, Allegri V, Grassetto G, Rubello D, Nanni C, Franchi R.
Biomed Pharmacother. 2008 Mar 3. [Epub] PMID: 18358680
Link to Abstract
Antitumor Activity of Rapamycin and Octreotide as Single Agents or in Combination in Neuroendocrine Tumors.
Moreno A, Akcakanat A, Munsell MF, Soni A, Yao JC, Meric-Bernstam F.
Endocr Relat Cancer. 2008 Mar;15(1):257-66. PMID: 18310292
Link to Abstract
Complete Response of CNS-Involved Olfactory Neuroendocrine Tumor using Multimodal Therapy.
Ahuja G, Cuellar S, Choudhry I, Setty S, Yao M, Villano JL.
Onkologie. 2008 Mar;31(3):119-21. PMID: 18322415
Link to Abstract
Assessment of the Efficacy and Toxicity of (131)I-Metaiodobenzylguanidine Therapy for Metastatic Neuroendocrine Tumours.
Nwosu AC, Jones L, Vora J, Poston GJ, Vinjamuri S, Pritchard DM.
Br J Cancer. 2008 Feb 19. PMID: 18283308
Link to Abstract
Treatment with Combined Streptozotocin and Liposomal Doxorubicin in Metastatic Endocrine Pancreatic Tumors.
Fjällskog ML, Janson ET, Falkmer UG, Vatn MH, Oberg KE, Eriksson BK.
Neuroendocrinology. 2008 Feb 18. PMID: 18285678
Link to Abstract
Is Laparoscopic Resection Adequate in Patients with Neuroendocrine Pancreatic Tumors?
Fernández-Cruz L, Blanco L, Cosa R, Rendón H.
World J Surg. 2008 Feb 11. PMID: 18264824
Link to Abstract
Islet 1 (Isl1) Expression is a Reliable Marker for Pancreatic Endocrine Tumors and Their Metastases.
Schmitt AM, Riniker F, Anlauf M, Schmid S, Soltermann A, Moch H, Heitz PU, Klöppel G, Komminoth P, Perren A.
Am J Surg Pathol. 2008 Feb 5. PMID: 18300808
Link to Abstract
Transcatheter Arterial Chemoembolization (TACE) Using Degradable Starch Microspheres (DSM) (DSM-TACE) for Primary and Metastatic Liver Neuroendocrine Tumors from Gastrointestinal Neuroendocrine Tumors.
Fujisaki T, Ikari T, Kamei A, Takano K, Kuraoka K, Yoshimoto K, Hirasawa T, Asahara S.
Nippon Shokakibyo Gakkai Zasshi. 2008 Feb;105(2):206-13. PMID: 18250591
Link to Abstract
Prognostic Factors at Diagnosis and Value of WHO Classification in a Mono-Institutional Series of 180 Non-Functioning Pancreatic Endocrine Tumours.
Bettini R, Boninsegna L, Mantovani W, Capelli P, Bassi C, Pederzoli P, Delle Fave GF, Panzuto F, Scarpa A, Falconi M.
Ann Oncol. 2008 Jan 21. PMID: 18209014
Link to Abstract
Report on Short-Term Side Effects of Treatments with (177)Lu-Octreotate in Combination with Capecitabine in Seven Patients with Gastroenteropancreatic Neuroendocrine Tumours.
van Essen M, Krenning EP, Kam BL, de Herder WW, van Aken MO, Kwekkeboom DJ.
Eur J Nucl Med Mol Imaging. 2008 Jan 11. PMID: 18188559
Link to Abstract
Laparoscopic vs Open Resection of Pancreatic Endocrine Neoplasms: Single Institution’s Experience over 14 Years.
Gumbs AA, Grès P, Madureira F, Gayet B.
Langenbecks Arch Surg. 2008 Jan 10. PMID: 18196267
Link to Abstract
Results Following Surgical Resection for Malignant Pancreatic Neuroendocrine Tumours. A Single Institutional Experience.
Bonney GK, Gomez D, Rahman SH, Verbeke CS, Prasad KR, Toogood GJ, Lodge JP, Menon KV.
JOP. 2008 Jan 8;9(1):19-25. PMID: 18182738
Link to Abstract
Functional MRI Evaluation of Tumor Response in Patients with Neuroendocrine Hepatic Metastasis Treated with Transcatheter Arterial Chemoembolization.
Liapi E, Geschwind JF, Vossen JA, Buijs M, Georgiades CS, Bluemke DA, Kamel IR.
AJR Am J Roentgenol. 2008 Jan;190(1):67-73. PMID: 18094295
Link to Abstract
Thymic Carcinoid Responds to Neoadjuvant Therapy with Sunitinib and Octreotide: A Case Report.
Dham A, Truskinovsky AM, Dudek AZ.
J Thorac Oncol. 2008 Jan;3(1):94-7. PMID: 18166847
Link to Abstract
Improved Contemporary Surgical Management of Insulinomas: A 25-Year Experience at the Massachusetts General Hospital.
Nikfarjam M, Warshaw AL, Axelrod L, Deshpande V, Thayer SP, Ferrone CR, Fernández-del Castillo C.
Ann Surg. 2008 Jan;247(1):165-72. PMID: 18156937
Link to Abstract
Pancreatic Neuroendocrine Tumours.
Alexakis N, Neoptolemos JP.
Best Pract Res Clin Gastroenterol. 2008;22(1):183-205. PMID: 18206821
Link to Abstract
Diagnostic Value of CDX-2 and TTF-1 Expressions in Separating Metastatic Neuroendocrine Neoplasms of Unknown Origin.
Lin X, Saad RS, Luckasevic TM, Silverman JF, Liu Y.
Appl Immunohistochem Mol Morphol. 2007 Dec;15(4):407-14. PMID: 18091383
Link to Abstract
Use of Octreotide for the Prevention of Pancreatic Fistula after Elective Pancreatic Surgery: A Systematic Review and Meta-Analysis.
Alghamdi AA, Jawas AM, Hart RS.
Can J Surg. 2007 Dec;50(6):459-66. Review. PMID: 18053374
Link to Abstract
Laparoscopic Enucleation of Insulinomas.
Sweet MP, Izumisato Y, Way LW, Clark OH, Masharani U, Duh QY.
Arch Surg. 2007 Dec;142(12):1202-4; discussion 1205. PMID: 18086988
Link to Abstract
Strategy for the Surgical Management of Insulinomas: Analysis of 52 Cases.
Liu H, Peng C, Zhang S, Wu Y, Fang H, Sheng H, Peng S.
Dig Surg. 2007;24(6):463-70. Epub 2007 Nov 29. PMID: 18057893
Link to Abstract
Clinicopathologic Features and Treatment Trends of Pancreatic Neuroendocrine Tumors: Analysis of 9,821 Patients.
Bilimoria KY, Tomlinson JS, Merkow RP, Stewart AK, Ko CY, Talamonti MS, Bentrem DJ.
J Gastrointest Surg. 2007 Nov;11(11):1460-7; discussion 1467-9. Epub 2007 Sep 11. PMID: 17846854
Link to Abstract
Diagnosis and Treatment of Gastric Neuroendocrine Tumours.
Plöckinger U.
Wien Klin Wochenschr. 2007 Nov;119(19-20):570-572. PMID: 17985089
Link to Abstract
Diagnosis and Treatment of Gastrinoma in the Era of Proton Pump Inhibitors.
Banasch M, Schmitz F.
Wien Klin Wochenschr. 2007 Nov;119(19-20):573-578. PMID: 17985090
Link to Abstract
Management of Sporadic and Multiple Endocrine Neoplasia Type 1 Gastrinomas.
Fendrich V, Langer P, Waldmann J, Bartsch DK, Rothmund M.
Br J Surg. 2007 Nov;94(11):1331-41. PMID: 17939142
Link to Abstract
Type 1 and 2 Gastric Carcinoid Tumors: Long-Term Follow-up of the Efficacy of Treatment with a Slow-Release Somatostatin Analogue.
Manfredi S, Pagenault M, de Lajarte-Thirouard AS, Bretagne JF.
Eur J Gastroenterol Hepatol. 2007 Nov;19(11):1021-5. PMID: 18049175
Link to Abstract
The Role of Somatostatin Analogues in the Treatment of Neuroendocrine Tumours.
Grozinsky-Glasberg S, Grossman AB, Korbonits M.
Mol Cell Endocrinol. 2007 Oct 13. PMID: 18037561
Link to Abstract
Embolization of an Insulinoma of the Pancreas with Trisacryl Gelatin Microspheres as Definitive Treatment.
Rott G, Biggemann M, Pfohl M.
Cardiovasc Intervent Radiol. Epub 2007 Oct 6. PMID: 17922161
Link to Abstract
Diagnosis and Surgical Treatment of Pancreatic Endocrine Tumors in 36 Patients: A Single-Center Report
Liu H, Zhang SZ, Wu YL, Fang HQ, Li JT, Sheng HW, Wang Y.
Chin Med J (Engl). 2007 Sep 5;120(17):1487-90. PMID: 17908455
Link to Abstract
Endocrine Pancreatic Tumors with Glucagon Hypersecretion: A Retrospective Study of 23 Cases During 20 Years.
Kindmark H, Sundin A, Granberg D, Dunder K, Skogseid B, Janson ET, Welin S, Oberg K, Eriksson B.
Med Oncol. 2007;24(3):330-7. PMID: 17873310
Link to Abstract
RadioFrequency Thermal Ablation of Metastatic Neuroendocrine Tumors in the Liver.
Mazzaglia PJ, Berber E, Siperstein AE.
Curr Treat Options Oncol. 2007 Aug;8(4):322-30. PMID: 18084730
Link to Abstract
Effective Treatment of Locally Advanced Endocrine Tumors of the Pancreas with Chemoradiotherapy.
Strosberg J, Hoffe S, Gardner N, Choi J, Kvols L.
Neuroendocrinology. 2007;85(4):216-20. PMID: 17541257
Link to Abstract
Successful Pancreatectomy with En-Bloc Resection of the Celiac Artery and Portal Vein for Pancreatic Endocrine Carcinoma.
Akatsu T, Aiura K, Shimazu M, Ueda M, Wakabayashi G, Tanabe M, Kawachi S, Shinoda M, Kameyama K, Kitajima M, Kitagawa Y.
Hepatogastroenterology. 2007 Jun;54(76):1269-71. PMID: 17629086
Link to Abstract
Magnetic poly epsilon-caprolactone nanoparticles containing Fe3O4 and gemcitabine enhance anti-tumor effect in pancreatic cancer xenograft mouse model.
Gang J, Park SB, Hyung W, Choi EH, Wen J, Kim HS, Shul YG, Haam S, Song SY.
J Drug Target. 2007 Jul;15(6):445-53. PMID: 17613663
Link to Abstract
Aggressive Pancreatic Resection for Primary Pancreatic Neuroendocrine Tumor: Is it Justifiable?
Teh SH, Deveney C, Sheppard BC.
Am J Surg. 2007 May;193(5):610-3; discussion 613. Oregon Health and Science University, Portland, Oregon.
Link to Abstract
Comparison of (68)Ga-DOTATOC PET and (111)In-DTPAOC (Octreoscan) SPECT in Patients with Neuroendocrine Tumours.
Buchmann I, Henze M, Engelbrecht S, Eisenhut M, Runz A, Schafer M, Schilling T, Haufe S, Herrmann T, Haberkorn U.
Eur J Nucl Med Mol Imaging. 2007 May 23. University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Link to Abstract
Temozolomide as Monotherapy is Effective in Treatment of Advanced Malignant Neuroendocrine Tumors.
Ekeblad S, Sundin A, Janson ET, Welin S, Granberg D, Kindmark H, Dunder K, Kozlovacki G, Orlefors H, Sigurd M, Oberg K, Eriksson B, Skogseid B.
Clin Cancer Res. 2007 May 15;13(10):2986-91. Uppsala University, Uppsala, Sweden
Link to Abstract
68Ga-DOTA-Tyr3-Octreotide PET in Neuroendocrine Tumors: Comparison with Somatostatin Receptor Scintigraphy And CT.
Gabriel M, Decristoforo C, Kendler D, Dobrozemsky G, Heute D, Uprimny C, Kovacs P, Von Guggenberg E, Bale R, Virgolini IJ.
J Nucl Med. 2007 Apr;48(4):508-18. Innsbruck Medical University, Innsbruck, Austria.
Link to Abstract
Surgery in Malignant Pancreatic Neuroendocrine Tumors.
Nguyen SQ, Angel LP, Divino CM, Schluender S, Warner RR.
J Surg Oncol. 2007 Apr 27. The Mount Sinai School of Medicine, New York, New York.
Link to Abstract
Surgical Strategies and Predictors of Outcome for Malignant Neuroendocrine Tumors of the Pancreas.
Bahra M, Jacob D, Pascher A, Plockinger U, Kristiansen G, Neuhaus P, Langrehr JM.
J Gastroenterol Hepatol. 2007 Apr 19. Humboldt University, Berlin, Germany.
Link to Abstract
Biochemistry of Neuroendocrine Tumours.
de Herder WW.
Best Pract Res Clin Endocrinol Metab. 2007 Mar;21(1):33-41. Sector of Endocrinology, Erasmus MC, 3015 CE Rotterdam, The Netherlands.
Link to Abstract
Imaging of Neuroendocrine Tumours (CT/MR/US).
Rockall AG, Reznek RH.
Best Pract Res Clin Endocrinol Metab. 2007 Mar;21(1):43-68. St Bartholomew’s Hospital, Dominion House, Bartholomew Close, West Smithfield, London, UK.
Link to Abstract
Race, Socioeconomic Status, Treatment, and Survival Time among Pancreatic Cancer Cases in California.
Zell JA, Rhee JM, Ziogas A, Lipkin SM, Anton-Culver H.
Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):546-52. University of California, Irvine Medical Center, Orange, California, USA
Link to Abstract
Surgery on Neuroendocrine Tumours.
Akerstrom G, Hellman P.
Best Pract Res Clin Endocrinol Metab. 2007 Mar;21(1):87-109. University Hospital, SE-751 85 Uppsala, Sweden.
Link to Abstract
Aggressive Surgery Improves Long-Term Survival in Neuroendocrine Pancreatic Tumors: An Institutional Experience.
Schurr PG, Strate T, Rese K, Kaifi JT, Reichelt U, Petri S, Kleinhans H, Yekebas EF, Izbicki JR.
Ann Surg. 2007 Feb;245(2):273-81. University Medical Center of Hamburg-Eppendorf, University of Hamburg, Germany.
Link to Abstract
Clinical and In Vitro Studies of Imatinib in Advanced Carcinoid Tumors.
Yao JC, Zhang JX, Rashid A, Yeung SC, Szklaruk J, Hess K, Xie K, Ellis L, Abbruzzese JL, Ajani JA.
Clin Cancer Res. 2007 Jan 1;13(1):234-40. The University of Texas / M.D. Anderson Cancer Center, Houston, Texas.
Link to Abstract
An Aggressive Surgical Approach Leads to Long-Term Survival in Patients with Pancreatic Endocrine Tumors.
Fendrich V, Langer P, Celik I, Bartsch DK, Zielke A, Ramaswamy A, Rothmund M.
Ann Surg. 2006 Dec;244(6):845-51; discussion 852-3. Philipps-University Marburg, Germany.
Link to Abstract
Are Capecitabine and Oxaliplatin (XELOX) Suitable Treatments for Progressing Low-Grade and High-Grade Neuroendocrine Tumours?
Bajetta E, Catena L, Procopio G, De Dosso S, Bichisao E, Ferrari L, Martinetti A, Platania M, Verzoni E, Formisano B, Bajetta R.
Cancer Chemother Pharmacol. 2006 Aug 26; [Epub]. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy.
Link to Abstract
Resection of Pancreatic Neuroendocrine Tumors: Results of 70 Cases.
Kazanjian KK, Reber HA, Hines OJ.
Arch Surg. 2006 Aug;141(8):765-9; discussion 769-70. University of California, Los Angeles.
Link to Abstract
Liver Transplantation for Patients with Metastatic Endocrine Tumors: Single-Center Experience with 15 Patients.
Frilling A, Malago M, Weber F, Paul A, Nadalin S, Sotiropoulos GC, Cicinnati V, Beckebaum S, Bockisch A, Mueller-Brand J, Hofmann M, Schmid KW, Gerken G, Broelsch CE.
Liver Transpl. 2006 Jul;12(7):1089-96. University Hospital Essen, Essen, Germany
Link to Abstract
Survival and Response after Peptide Receptor Radionuclide Therapy with [90Y-DOTA0,Tyr3]Octreotide in Patients with Advanced Gastroenteropancreatic Neuroendocrine Tumors.
Valkema R, Pauwels S, Kvols LK, Barone R, Jamar F, Bakker WH, Kwekkeboom DJ, Bouterfa H, Krenning EP.
Semin Nucl Med. 2006 Apr;36(2):147-56. Department of Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.
Link to Abstract
Efficacy and Tolerability of Pegylated IFN-alpha in Patients with Neuroendocrine Gastroenteropancreatic Carcinomas.
Pavel ME, Baum U, Hahn EG, Schuppan D, Lohmann T.
J Interferon Cytokine Res. 2006 Jan;26(1):8-13. University Hospital Erlangen-Nuremberg, 91054 Erlangen, Germany.
Link to Abstract
Phase II Study 0f Temozolomide and Thalidomide in Patients with Metastatic Neuroendocrine Tumors.
Kulke MH, Stuart K, Enzinger PC, Ryan DP, Clark JW, Muzikansky A, Vincitore M, Michelini A, Fuchs CS.
J Clin Oncol. 2006 Jan 20;24(3):401-6. Dana-Farber Cancer Institute, Boston, Massachusetts.
Link to Abstract
The Role of Cytoreductive Hepatic Surgery as an Adjunct to the Management of Metastatic Neuroendocrine Carcinomas.
Hodul P, Malafa M, Choi J, Kvols L.
Cancer Control. 2006 Jan;13(1):61-71. H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.
Link to Abstract
Targeted Radionuclide Therapy with 90Y-DOTATOC in Patients with Neuroendocrine Tumors.
Forrer F, Waldherr C, Maecke HR, Mueller-Brand J.
Anticancer Res. 2006 Jan-Feb;26(1B):703-7. University Hospital Basel, Switzerland.
Link to Abstract
