Pancreatic cancer remains underfunded !
CONFRONTING PANCREATIC CANCER
Pancreatic Cancer Topics of Interest
The pancreas is a small, spongy organ which lies just under the curvature of the stomach and deep within the abdomen. The function of the pancreas is a complicated, but one could say that it primarily does two things …
There are no universally agreed upon firm guidelines for medical treatment for those patients with pancreatic cancer who are not candidates for surgery or who have a recurrence of the cancer after surgical resection…
Surgery for adenocarcinoma of the pancreas is only offered to patients whose tumor is localized and meets other criteria (please note earlier FAQ topics). Only about 15-20% of those individuals with pancreatic cancer will be found to be eligible for surgery…
Pancreatic cancer in the early stages typically causes vague nonspecific symptoms. These symptoms and signs may include poor appetite, weight loss, abdominal or back pain, Jaundice (yellowing of the eyes or skin, dark colored urine and/or light colored bowel movements) …
The true specific cause of pancreatic cancer in an individual is generally never known. But there are population level studies which demonstrate associations between specific behaviors or characteristics and pancreatic cancer. And pancreatic cancer is more common in some families …
Neuroendocrine tumors of the pancreas (islet cell tumors) including carcinoid tumors are much less common than tumors arising from the exocrine pancreas. Reports often indicate that there are about two to three thousand cases diagnosed in the U.S. each year…
Preliminary findings of a Phase III U.S. clinical trial with the orally administered FDA-designated “orphan drug” daraxonrasib, which acts as a selective RAS genetic (mutation) inhibitor (present in more than 90% of those with pancreatic cancer) were reported out by the clinical oncology Revolution Medicines company in a press release in April 2026.
The results were highly encouraging in that those in the study (all with previously treated advanced ductal adenocarcinoma of the pancreas) who received just the oral daraxonrasib alone (daily, 300 mg) doubled their overall survival duration to 13.2 months as compared to those who otherwise received standard chemotherapy (6.7 months).
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Pancreatic cancer, one of the least funded and most challenging cancers, has long held a daunting prognosis. However, we hold onto hope and strive for a future where early diagnoses and effective treatments are commonplace. We understand the increase in pancreatic cancer cases and its prediction to become the second leading cause of cancer-related death in the U.S. by 2030 is alarming. Pancreatica.org stands as a beacon of light, providing timely information and support to those in need, fervently focusing on bolstering research for early diagnosis.
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The incidence of African Americans who get pancreatic cancer is 50-90% higher than the general population in the United States. Studies have shown that African Americans are more likely than any other race to get pancreatic cancer. They are also twice as likely to be diagnosed with late-stage pancreatic cancer. At every disease stage, African Americans demonstrate poorer outcomes including increased mortality rates from pancreatic cancer . . .
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